In early January 2026, the U.S. Cybersecurity and Infrastructure Security Agency (CISA) made a sobering addition to its Known Exploited Vulnerabilities (KEV) catalog by listing two significant security flaws that are being actively abused by threat actors.
One is a modern, critical flaw in Hewlett Packard Enterprise’s (HPE) OneView infrastructure management software with a maximum severity score, and the other is a legacy Microsoft Office PowerPoint vulnerability that has somehow lingered into the present day with ongoing exploitation. The real message for business leaders is simple: vulnerabilities left uncontained become windows for compromise, and traditional "detect and respond" security models are no longer enough.
A Maximum Severity Threat in Modern Infrastructure
The headline vulnerability, tracked as CVE-2025-37164, resides in HPE OneView, a widely deployed solution that centralizes management for servers, storage, and networking infrastructure. With a CVSS score of 10.0, this unauthenticated remote code execution flaw enables attackers to potentially take full control of affected environments if they can reach the vulnerable service. What makes this even more alarming is that CISA’s inclusion of the flaw in its actively exploited catalog means real-world abuse has been confirmed, urging all organizations to treat this as an imminent risk.
According to threat intelligence and advisories from security researchers, weaponized exploit code is publicly available, significantly lowering the bar for attackers—from sophisticated actors to opportunistic adversaries looking to gain unauthorized access. In environments where OneView serves as a control plane, successful exploitation could allow manipulation of firmware and system configuration at scale.
An Old Office Flaw Still in Play
Perhaps equally surprising is that CVE-2009-0556, a code injection vulnerability in Microsoft Office PowerPoint originally disclosed back in 2009, has reappeared on CISA’s list of actively exploited vulnerabilities. Despite being patched years ago, the fact that it’s still appearing in real-world attacks suggests that unsupported systems or legacy Office installations remain a meaningful attack vector for cybercriminals.
This illustrates a perennial challenge in cybersecurity: old vulnerabilities never truly disappear until every system is fully patched or retired. For many organizations, legacy systems that run unpatched software become stepping stones for attackers to compromise broader networks.
Why This Matters to Business Owners
Both of these vulnerabilities demonstrate a clear trend: attackers will exploit whatever weaknesses they can find, whether they are bleeding edge or over a decade old. And until organizations move beyond simply detecting and responding to threats, they will always be playing catch-up.
Traditional detection-focused defenses can alert security teams after an intrusion has already begun. Yet, by the time alerts trigger, data theft, ransomware deployment, or systems compromise may already be underway.
Modern endpoint security demands a different approach—one that inherently prevents exploitation, isolates threats immediately, and contains malicious activity before it can spread.
The Case for Moving from Detect and Respond to Isolation and Containment
This is where solutions like AppGuard come into play. With a 10-year track record of proven endpoint protection, AppGuard does not rely on detecting threats after they manifest. Instead, it uses isolation and containment techniques to block exploit attempts at the point of execution. Rather than waiting for signatures or behavioral indicators, AppGuard stops unknown and known exploit activity alike by confining processes and applications to safe execution boundaries.
This approach is crucial when dealing with the kind of vulnerabilities flagged by CISA. Whether it’s a freshly discovered critical flaw in enterprise infrastructure software or a long-forgotten Office vulnerability, containment-first security ensures that exploit code cannot run freely even in unpatched or unpredictable environments.
Take Action Today
Business owners must recognize that cyber threats are evolving faster than traditional defenses. Waiting for detection and then reacting is no longer sufficient to protect your company’s most valuable assets.
Talk with us at CHIPS about how AppGuard can help your organization move beyond detect-and-respond strategies and toward true prevention through isolation and containment. Let’s ensure your business is protected against active exploitation like the HPE OneView and PowerPoint vulnerabilities that CISA has just flagged—before they become your next breach.
Contact CHIPS today and secure your endpoints with a proven solution that stops threats in their tracks.
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